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Dominant Symptoms of Polycystic Kidney Disease

2012-09-13 16:04

Polycystic Kidney Disease, referring to both Autosomal Dominant Polycystic Kidney Disease (ADPKD) and Autosomal Recessive Polycystic Kidney Disease (ARPKD), brings sufferers lots of symptoms.

ARPKD symptoms

ARPKD is a rare kidney disorder which usually occur in infant. In cases of ARPKD, about a half of patients die of kidney failure or respiratory failure within several days or even several hours after their born. Therefore, there is no specific symptoms among these patients.

As for another half of ARPKD patients, they may live to adult, and for them, the major symptom is portal hypertension.

ADPKD symptoms

ADPKD is a common monogenic inherited kidney disorder with morbidity one in 1000 to one in 4000. ADPKD, mostly, appears when patients grow up to their 30 to 50, so it is always called Adult Polycystic Kidney Disease. ADPKD is a chronic kidney disease and with the progression of this disease, patients suffer more and more symptoms.

At the very beginning of this disease, patient may have no symptoms at all, but with the decrease of kidney function, the following symptoms will appear gradually.

1. High blood pressure

2. Frequent urination

3. Back pain/loin pain/backache/kidney pain

4. Urinary tract infections

5. Blood urine/hematuria

6. Foamy urine/proteinuria

7. Kidney growth

8. Renal anemia

9. Drowsiness, fatigue, poor appetite and poor concentration

10. Kidney stone/kidney calculi

Due to different illness condition, Polycystic Kidney Disease patients may suffer some or all the above symptoms. Without timely control, these symptoms become more and more serious and in return, they worsen kidney damages. Therefore, even if these symptoms appear because of Polycystic Kidney Disease, bringing them under control is of primary significance for halt PKD progresses to kidney failure.


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