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Treatment for Chronic Interstitial Nephritis

2012-10-26 16:55

Interstitial Nephritis is a kidney disorder characterized by swelling in between renal tubules. Main job of the kidneys is to filter bloodstream. Renal tubules function to reabsorb water and important organic substances from the kidney filtrate and secreting some substances into bloodstream. Chronic Interstitial Nephritis is gradual damage to renal interstitial caused by various inducing causes. It should be distinguished from acute Interstitial Nephritis wherein the onset is quite sudden and may give rise to acute kidney failure.

Treatment for chronic Interstitial Nephritis should be as early as possible, since if not treated timely or managed properly renal condition can deteriorate fast to advanced stage of chronic kidney failure. Clinically, the treatment for chronic Interstitial Nephritis is dependent upon the underlying cause of the kidney damage, the severity of kidney damage, the age of the patient and other health problems that the patient might have.

Chronic Interstitial Nephritis typically causes renal tubular dysfunction, symptoms of which mainly include proteinuria, high blood pressure, increased night urination, hypokalemia, etc. The disease can occur by various medical conditions as follows:

﹡Genetic kidney disorders, such as familial Interstitial Nephritis, Polycystic Kidney Disease (PKD), hereditary nephritis, etc;

﹡Certain Nephrotoxic medicines, such as non-steroidal anti-inflammatory drugs and Aristolochia medicines;

﹡Urinary tract diseases, including Obstructive Nephropathy and Reflux Nephropathy

﹡Infectious diseases, such as chronic renal pelvic nephritis caused by various Pathogens

﹡Physical damages, such as radioactivity associated kidney disease

﹡Immune disease, such as systemic Lupus Erythematosus, chronic transplant rejection damage, metabolic diseases, Multiple Myeloma, etc

Clinical treatment for Chronic Interstitial Nephritis mainly includes the following aspects:

﹡Treatment for underlying cause, which includes cessation of causative agents, management of autoimmune diseases and getting rid of obstructive factors

﹡Symptom-targeted treatment, including correcting renal ischemia, electrolyte imbalances and PH, etc

﹡Promote the regeneration of renal tubules. Cordyceps sinensis is beneficial for promoting growth of renal tubular epithelial cells, improving stability on cellular membrane, intensifying resistance to anoxia on renal tubular epithelium, thus assisting in treatment of chronic Interstitial Nephritis

﹡Immunosuppressant treatment. Immunosuppressive medication treatment can be applied to cases of chronic interstitial nephritis which is caused by autoimmune diseases and allergy to drugs

﹡Slow down deterioration of renal interstitial fibrosis. Those with accompanying high blood pressure can be prescribed anti-hypertensive medicines or low protein diet to delay progression of the disease

The above is general introduction for the treatment of Chronic Interstitial Nephritis. Clinically, how to treat the disease and the nursing care guidance should be based on the specific inducing cause and illness condition. If you have any difficulty in controlling the disease, you may consult our online experts for free.


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