How Does Glomerulonephritis Lead To Proteinuria

How does glomerulonephritis lead to proteinuria? Proteinuria is a presence of excess protein in urine (more than 150mg/24h). It is the most dominant symptom of glomerulonephritis. If not treated effectively, it will aggravate illness condition and accelerate glomerulonephritis to kidney failure. Therefore, almost all the patients know well about the importance of treating proteinuria. but unfortunately, few of them know how glomerulonephritis lead to proteinuria.

How does glomerulonephritis lead to proteinuria?

Glomerulonephritis is a kidney disorder marked by inflammation of the glomeruli or small blood vessels in kidney. Glomerulus is the filter of blood and works through mechanical barrier and charge barrier. For mechanical barrier, it only allows substances with small molecular weight to pass through. In this ways, macromolecular substances and some middle molecular substances are kept in blood effectively. And for charge barrier, it can help to kept substances with negative charge in blood and protect them from being leaked out. Under the effects of mechanical barrier and charge barrier, most of the substances in blood can be kept in our body and only a small amount of substances like urea and creatinine are leaked into urine finally.

For people with glomerulonephritis, inflammation cause damages on glomeruli and make them unable in performing filtration function. For this reason, many nutrition like protein which should be kept in the body leak into urine, leading to proteinuria. And also, usually the serious the kidney damages are, the more protein there are in urine and also the more severe the proteinuria is.

How to treat proteinuria caused by glomerulonephritis?

For glomerulonephritis patients, protein leak into urine due to injured glomerular filtration membrane. Seeing from this point of view, repairing injured glomeruli is of great importance. This is imperative for glomerulonephritis patients to treat proteinuria, but it is not the only part that patients need to do. In general, aside from repairing injured glomeruli, patients also need to:

1. Calculate protein intake

High protein intake increases kidney burden and worsen kidney condition, which can aggravate proteinuria. For glomerulonephritis patients, they need to calculate their protein intake, so as to avoid causing further increase of protein in urine. With different illness condition, patients need to ingest different amounts of protein everyday and this is closely based the residual kidney function as well as severity of proteinuria. (Leave your illness condition or send your test reports to kidneycares@hotmail.com, our experts will help to analyze illness condition and offer free suggestions about how much protein to ingest everyday)

2. Bring all the symptoms under control

In cases of glomerulonephritis, many symptoms like high proteinuria and hematuria can cause deterioration of illness condition, so having tight control about these symptoms will be an important part in treating proteinuria.

3. Block inflammation

Inflammation is the most direct cause of kidney damages, so blocking inflammation timely will help to avoid further kidney damages, which is also very essential for treating proteinuria.

Lastly, although proteinuria is just a symptom of glomerulonephritis, it is necessary for patients know well how glomerulonephritis lead to proteinuria. In cases of glomerulonephritis, no matter for proteinuria or other symptoms, only when the root cause of it is removed effectively, can the symptoms be solved fundamentally.