How to Reverse Interstitial Nephritis or Not Have It Worsened

Interstitial nephritis is also called renal tubular interstitial nephritis. It can be divided into acute and chronic interstitial nephritis.

In case of acute interstitial nephritis, elimination of underlying causes, timely and proper treatment can help recover the disease or reverse certain renal damages. As for chronic interstitial nephritis, it may take longer time and it is more difficult to reverse renal damages or recover renal functions.

To have effective treatment, the first step is to find out what is the exact cause of interstitial nephritis. The following are the common causes of renal tubular interstitial impairments.

· genetic diseases such as familial interstitial nephritis, polycystic kidney disease, medullary cystic disease, genetic nephritis, etc.

·certain drugs can cause renal damages such as non-steroidal anti-inflammatory drugs, aristolochic acid drugs, ciclosporin, etc. Therefore more cautions should be made before taking any drugs or medications especially over-the-counter drugs. It is better to take these drugs under the doctor’s guidance and tell your doctor if you have already developed some kidney problems.

·urinary tract diseases such as obstructive nephropathy, reflux nephropathy, etc.

·infectious diseases such as chronic nephropyelitis, etc.

·systemic diseases such as immune diseases like lupus, sicca syndrome, cryoglobulinemia, chronic graft rejections; metabolic diseases like high uric acid, high serum calcium, low serum potassium; blood diseases can all damage the renal tubules and cause interstitial nephritis.

According to different causes of interstitial nephritis as well as the severity of interstitial lesions and residual kidney functions, the prognosis and recovery rate is different. The following are some factors that can affect the prognosis of interstitial nephritis: elderly patients especially those that have hypertension or diabetes; renal tubular necrosis; the severity of renal interstitial fibrosis, etc. In case of the above mentioned conditions, renal damages can not be completely reversed and renal functions can not be completely recovered.

However, early and effective treatment can help preserve the residual kidney functions to the hilt. According to the underlying cause of renal damages and the severity of interstitial impairment, different treatments are available. For more detailed information about proper treatment for your specific interstitial nephritis, welcome to consult our online doctors or leave us a message.