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Prognosis of Membranous Nephropathy with Nephrotic Syndrome

2014-02-02 16:44

Membranous nephropathy is a kidney disorder in which glomeruli become inflamed. Nephrotic syndrome is a common complication of membranous nephropathy. How is the prognosis of membranous nephropathy with nephritic syndrome?

Membranous nephropathy with nephritic syndrome

Glomeruli are the basic functional units in kidneys. Each kidney is composed of around one million glomeruli. In right condition, the glomeruli can filter out waste products from body. However, in membranous nephropathy, the glomeruli become inflamed and scarred. Without effective treatment, the glomeruli will become leaky. A large amount of proteins will pass through glomeruli and end up in urine. Excessive loss of protein in urine will lead to nephritic syndrome.

Prognosis of membranous nephropathy with nephritic syndrome

The prognosis of membranous nephropathy with nephritic syndrome varies from individual to individual as it is affected by various.

Generally, the prognosis of membranous nephropathy is not very good, especially those with loss of heavy protein in urine. This is because the proteinuria can impair the kidney structure significantly.

In addition, other complications of membranous nephropathy also can affect the prognosis significantly like high blood pressure, anemia and so forth.

Treatment plays the key role in affecting the prognosis of membranous nephropathy. Steroid therapy is the most common therapy for the disease. It can suppress the inflammation in kidneys and reduce the permeability of small blood vessels in kidneys. Hence, it can reduce the leakage of protein in urine. However, it can not prevent the relapse of membranous nephropathy and renal function decline.

To improve the prognosis of membranous nephropathy with nephritic syndrome effectively, immunotherapy is the recommended treatment. This therapy can treat the disease by suppressing the inflammation in kidneys and rebuilding normal immune system. Hence, it can stop renal function from worsening. In addition, it can activate the self-healing system of the body to repair the impaired glomeruli. When renal function is improved, the prognosis of membranous nephropathy with nephritic syndrome will be improved remarkably.

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