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How to Improve GFR in Lupus Nephritis

2013-12-30 11:20

Lupus nephritis is one of serious complications of lupus.It is a progressive kidney disorder.As the condition progresses,GFR will decline gradually.How to improve GFR in lupus nephritis?

Reduced GFR in lupus nephritis

Lupus is an autoimmune disorder in which the immune system of the body attacks kidneys by mistakes.Immune system is a protective system of the body and it can protect the body against outside harmful substances.However,in lupus,it fails to function properly and can not distinguish the harmful substances from the healthy tissues and cells of the body.In Lupus Nephritis,the immune system attacks kidneys mistakenly. The abnormal activity of immune system can cause inflammation in kidneys.Without aggressive treatment,the inflammation may worsen renal function.Less blood will be filtered by glomeruli. Hence,reduced GFR will be the result and high levels of waste products will build up in body.

How to improve GFR in lupus nephritis?

The first treatment step is to stop renal function from declining further.Lupus is the underlying cause of kidney damage and reduced GFR in lupus nephritis.One of treatment goals for lupus nephritis with lower GFR is to control lupus. Apart from the general steroids and immunosuppressive agents, Immunotherapy is an effective treatment for lupus and it can control lupus fundamentally by correcting immune dysfunction and rebuilding normal immune system of the body.Hence,no more immune damage to kidneys will occur.

To improve GFR in lupus nephritis,an treatment should be applied to restore the impaired kidney structure.Stem Cell Therapy can improve GFR and enhance renal function by replacing the necrotic renal functional cells.

Stem cells are a group of immature cells and they can differentiate into various kinds of cells that body needs in right condition. In treating lupus nephritis, stem cells can divide into new cells to replace the necrotic renal cells. If the kidney structure can be restored, GFR will be improved remarkably and fundamentally in lupus nephritis.

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