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Focal Segmental Glomerulosclerosis (FSGS) in End-Stage Kidney Disease (ESRD)

2012-11-22 10:35

Some patients ask “what can I do when end-stage kidney disease lead to Focal Segmental Glomerulosclerosis (FSGS)”. End-stage kidney disease is the kidney failure stage which means remaining glomerular filtration rate is below 15. And Focal Segmental Glomerulosclerosis (FSGS) describes the appearance of kidney under biopsy with severe scarring on the filters of the kidneys. You may still be confused what this means, so in the following I will introduce about Focal Segmental Glomerulosclerosis (FSGS) and proper treatment for it.

Focal Segmental Glomerulosclerosis (FSGS) in End-Stage Kidney Disease (ESRD)

Focal Segmental Glomerulosclerosis (FSGS) is a pathological diagnosis of kidney disease. Glomerulis are basic filtering cells of the kidneys. Focal means some of the glomerlis are involved, and scarring means part on each glomerulus is damaged. Each Glomerular filter of the kidneys is made of three layers of cells that filter bloodstream freely and discharge wastes out of the body. Many types of kidney disorders, such as Diabetic Nephropathy, Purpura Nephritis, Lupus Nephritis, could cause scarring on the glomerular cells and cause FSGS. If those filtering cells are damaged, most patients experience proteinuria, hematuria, high blood pressure, etc.

If people with end-stage kidney disease take a renal biopsy, many will be detected Focal Segmental changes of their glomerulis. Kidney failure which is the end-stage of kidney disease means that a large part of functioning kidney cells is damaged and only some percentages of cells are still functioning. FSGS finding on ESRD will provide some proof for how much functioning cells exist. In a biopsy, if nine in ten cells are scarred this may be a sign for poorly functioning kidneys and poor prognosis.

Treatment for Focal Segmental Glomerulosclerosis (FSGS) in End-Stage Kidney Disease (ESRD)

If FSGS is not controlled in ESRD, the remaining renal cells can also get gradually atrophic so that the scarring further worsens to the point patients have to do dialysis to transplantation to survive. As of now, it is important that FSGS is controlled from deteriorating and the scarred kidneys can get improved. The treatment for reversing dead renal cells is difficult, but some herbal medicine treatment could help to repair the injured glomerular cells so that the kidneys can be improved and complications/symptoms will be controlled as well.

In addition, management of blood pressure, controlling blood lipids, reliving renal anemia and proper nutrition support will be needed under the instructions of an expert doctor. Now you may also consult us directly.

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