IgA Nephropathy, 30 Years Old, Male: What Is the Best Treatment

A:

Doctor: IgA Nephropathy is commonly called Berger’s disease. It is a glomerular disease with a number of IgA deposition in mesangial area. The clinical manifestations of IgA Nephropathy include repeated hematuria or microscopic hematuria, proteinuria in different severity, high blood pressure and renal insufficiency.

Occurrence of IgA Nephropathy is closely related with IgA deposition which usually occurs when immune system is abnormal or immunity is lower. In this light, we can know clearly IgA Nephropathy is an immune-related disease, so the treatment for IgA Nephropathy should be started from improving immune system and increase immunity.

In many cases of IgA Nephropathy, many patients are prescribed with oral medicines like cyclophosphamide and prednisone after the diagnosis. These medicines are effective in controlling hematuria and proteinuria symptoms and they can help to remit illness condition in some ways. However, all these medicines only focus on symptoms and can not remove IgA deposition away from the kidney, which lead to the repeat relapse of disease. Besides, long-term taking of these medicines can restrain immunity and impair immune system. Therefore, it is far from enough for IgA Nephropathy patients to get radical recovery by simply controlling symptoms.

IgA Nephropathy is a chronic kidney problem and it can progress to kidney failure over time if we do not stop it fundamentally. IgA deposition in kidney cause inflammation which damage our kidney directly, so it is necessary to block inflammation. However, after the blocking, we also need to clear IgA deposition away from the kidney as well as improve immune system so that no more IgA deposition are formed again. Only with this systematic and scientific treatment method, can IgA Nephropathy be stopped from the root.