Q:
My mother is now in stage 5 chronic kidney disease and her creatinine is now about 480. What will high creatinine cause and what can you advice for my mother? And by the way my mother has 2 years history of diabetes.
A:
Creatinine is the metabolic product of muscles in the body and it is mainly discharged out of the body through the filtration of the kidneys. As for the normal value of creatinine, it is about 44-133umol/L for male and 70-108umol/L for female. Since it has much to do with muscle metabolism, the normal level might be lowered in the elderly.
Persistent increased level of serum creatinine indicates substantial damages of the kidney functions and creatinine level of 451umol/L means that the illness has progressed into the stage of renal failure and usually creatinine of 500 will need dialysis to help discharge the excessive accumulation of wastes and toxins in the body or they will cause many symptoms and complications.
The following are the possible symptoms and complications of high creatinine of 480
Edema
High blood pressure
Urinary frequency, urinary urgency and urinary pains
Back pain
Blood in urine
Bubbles in urine
Increased night urination
Heart failure
Loss of appetite
Nausea, vomiting
Fatigue
Headache
Restless or even coma
Hyperuricemia
Hyperlipidemia
Hypoalbuminemia, etc
Advices for high creatinine of 480
Diets: limit the daily intake of salt and protein and have more foods that are rich in vitamins.
Treatments: if the patients have severe discomforts and symptoms, dialysis is needed to get rid of the life-threatening risk factors. And in the stage of clinical remission, some herbal medicines can be used to regulate the disorders in the body and improve the kidney functions.
And since your mother has diabetes, it is also vey important to bring the blood sugar well under control or high level of blood sugar will cause further kidney damages.