Is Diphenhydramine Contraindicated In IgA Nephropathy Patients

Diphenhydramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Acute kidney injury can be caused by a commonly used over-the counter and prescription medication, diphenhydramine. Thus, diphenhydramine is contraindicated in IgA Nephropathy patients.

IgA Nephropathy is an autoimmune disease that affects the kidneys. After many years, IgA deposits may cause the kidneys to leak blood and sometimes protein in the urine.

How to treat IgA Nephropathy?

1. High blood pressure

High blood pressure damages the kidneys. Two types of hypotensive medicines called angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs). These medicines can not only lower blood pressure but also reduce protein loss in the urine. Due to this affect, they are often used in IgA Nephropathy to protect the kidneys.

2. High cholesterol

Through proper diet and taking medicine, they can help lower high cholesterol level. Lowering cholesterol levels may help slow kidney damage.

3. Prednisone

Prednisone is one of the most common medicine for IgA Nephropathy. However, long term use of this medicine have harmful side effects.

4. Immunotherapy

Immunotherapy can treat IgA Nephropathy more radically. This therapy consists of six steps: Immune diagnosis, Immune blocking, Immune tolerance, Immune regulation, Immune clearance and immune protection. In Immunotherapy, various western medicines are used to control symptoms of IgA Nephropathy and show quick and obvious therapeutic effects. When patients’ illness conditions get stable, Chinese medicines are used. To make Chinese medicines work fully and efficiently, Micro-Chinese Medicine Osmotherapy is created. The active ingredients in Chinese medicines can expand blood vessels, block inflammation and coagulation, and degrade extracellular matrix. All these are essential for IgA Nephropathy to recover. With the help of Chinese medicines, immune system can be normalized and immunity can be enhanced, which can help prevent the formation of new IgA complexes.

Diphenhydramine is contraindicated in IgA Nephropathy. Immunotherapy is recommended for patients with IgA Nephropathy. We hope you can seize the chance to treat your disease timely.