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Creatinine Increases after Kidney Transplant in IgA Nephropathy

2013-11-24 09:59

IgA nephropathy is an autoimmune disorder in which the immune system attacks the kidneys mistakenly.When kidneys fail to function,kidney transplant will be applied.However,in some cases,IgA nephropathy may return to the new kidney,resulting in high Creatinine.

Why does IgA nephropathy relapse after Kidney Transplant?

Immune system is a powerful protective system in body.When outside harmful substances invade into body,immune system will be initiated to produce antibodies to defeat them.However,in autoimmune disease,the immune system fails to function properly.After the harmful substances are eliminated,the immune system activity can not cease.As a result,excess antibodies are produced.In IgA Nephropathy,excess immunoglobulin A ( IgA) is produced.With blood circulation,IgA will deposit in mesangial area.To eliminate IgA from kidneys, an inflammation is initiated.The inflammation can impair kidneys, resulting in progressive renal function decline.

Kidney transplant is a procedure in which the diseased kidney is replaced with a new kidney.However,the transplant can not correct immune dysfunction.After kidney transplant,the immune system may attack the new kidney again.Hence,IgA nephropathy will recur to the new kidney.When kidneys are not functioning properly,high creatinine will be the result.

Treatment for IgA nephropathy after kidney transplant

To treat IgA nephropathy after kidney transplant,the patients should have a treatment to rebuild normal immune system and restore the impaired kidney structure.The combined therapy of immunotherapy and Micro-Chinese Medicines Osmotherapy is applied to people with IgA nephropathy.

Immunotherapy is a therapy in which the body use the immune system to treat diseases.In treating IgA nephropathy,it can correct the immune dysfunction and help the body rebuild normal immune system. If so, the immune system will return to protect the body against harmful substances.

Micro-Chinese Medicines Osmotherapy can activate the self-healing system of the body. If the impaired kidney tissues can be repaired, the kidney damage will be reversed. If so, IgA nephropathy will be controlled fundamentally.

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