Auto Immune Disease That Cause IgA Kidney Disease

IgA kidney disease is also called IgA nephropathy or Berger’s disease. It is an auto-immune disease due to immune disorders and deposition of immune complexes in the kidneys.

Immune disorders and immune dysfunction cause accumulation of immune complexes in the body. These immune complexes will circulate in the body with blood. When the blood flows into the kidneys, immune complexes will deposit in glomerular mesangial areas and cause renal damages, resulting in a series of symptoms such as proteinuria, hematuria, swelling, high blood pressure, declined renal functions, etc.

For auto-immune diseases, traditional medicines and treatments are not very effective especially from the long run because they can not solve the very root problem. On the contrary, long term use of steroids and immunosuppressants will further weaken the immune system and worsen renal damages.

Immunotherapy is a breakthrough that is found to be effective at treating auto immune diseases including IgA kidney disease. Immunotherapy can be divided into 6 steps and not all these steps will be involved for each patient. A thorough and exact diagnosis will be done to make clear the location and severity of renal damages so as to provide guidance for the following treatment.

Steroids and immunosuppressants will also be used, but patients will not become dependent on them and the side effects of these drugs are much reduced because they are just one small step of the whole treatment. They are used temporarily relieve symptoms. More effective treatment will be adopted to repair damaged renal tissues so as to recover renal structure and improve renal functions. Medicines that can help regulate immune disorders and enhance immunity will also be used to help solve the very root problem for IgA nephropathy patients.

Immunotherapy can regulate immune disorder so that the production of immune complexes can be reduced or they can be removed from the blood. Immune deposition in the kidneys can be degraded and removed from the kidneys. This helps prevent further renal damages. Immunotherapy can provide essential nutritions for repairing damaged renal tissues and improving renal functions. This can also help protect the kidneys from potential damages due to immune disorders.