Will IgA Nephropathy Cause Decrease of Urine Volume

Will IgA nephropathy cause decrease of urine volume? Many causes can lead to decline of urine volume, for instance, dehydration, vomiting, diarrhea, fever, etc. These causes are mostly common for people to have decreased urine volume. However, there are still some diseases which can cause decreased urine output, such as: cancer, kidney disease, amyloidosis, multiple myeloma. The research shows that some patients with IgA nephropathy have the symptom of decreased urine output. Many people are concerned that if IgA nephropathy has necessary connection with decline of urine volume. Here we will discuss about this question.

Primarily, we give you an exact answer, that yes, IgA nephropathy can cause decline of urine output. Then let’s see how the urine is produced and how decrease of urine output is caused by IgA nephropathy.

How is the urine produced?

Blood in body flows into kidneys, and kidneys can filter wastes and fluids out of blood by functions of glomerulus and kidney tubules. Then these wastes and fluids are eliminated from the body in liquid urine. In this way, urine is produced.

From the above, we can know that in fact, urine is composed of these wastes and fluids.

How can IgA nephropathy cause decrease of urine volume?

For patients with IgA nephropathy, as IgA which is an antibody deposits in glomerular mesangial area, body makes inflammatory reaction in this area. In this way, glomerulus is impaired and filtration of glomerulus is affected. Thus, glomerulus can’t remove large quantities of wastes and fluids in blood from body. The less wastes and fluids glomerulus removes, the less the urine is produced.

Besides, IgA nephropathy can lead to kidney failure, which means the whole kidney function will be affected, so kidneys can only remove much less wastes and fluids from body and urine volume may decreases largely.

Patients with IgA nephropathy should pay much attention to decreased urine volume, because urine output can be regarded as an indicator that how severe kidney function is. If patients with IgA nephropathy have obvious decline of urine output, they should get effective treatment in time.