Swollen Ankles And Protein in Urine in IgA Nephropathy

IgA nephropathy is an autoimmune disorder with deposits of immunoglubulin A (IgA) in mesangial area.It is a progressive disorder and a host of symptoms will appear as renal function decline.Swollen ankles and protein in urine are two typical signs in IgA nephropathy.

Protein in urine in IgA nephropathy

Protein is an important substance in the human body.It is a major source of energy and also involve the creation of some hormones.Also it forms antibodies that help prevent infection, illness and disease etc.Just list a number of important functions of protein here.

In right condition,the kidneys can filter out wastes and extra fluid from body,but can preserve useful substances in body. However,in IgA nephropathy,the kidneys fail to function properly and a large amount of proteins will leak into urine through kidneys, thus resulting in protein in urine.

Swollen ankles in IgA nephropathy

Protein in urine can be an attributable factor of swollen ankles in IgA nephropathy.Protein is just like a sponge and can hold fluid in blood vessels.Lower levels of protein in blood vessels will not hold fluid in blood vessels as before.As a result,a large amount of fluid will infilter into subcutaneous tissue,thus resulting in swelling.

In addition,fluid retention in body also can contribute to swollen ankles in IgA nephropathy.One of important kidney functions is to filter out extra fluid from body to keep the standard content of fluid in body.However,when kidneys fail to function adequately,the extra fluid can not be removed from body,thus resulting in extra fluid retention in body.Due to gravity,the swelling often firstly occurs in lower body parts like legs.That is how swollen ankles occur in IgA Nephropathy.

The above are the causes of swollen ankles and protein in urine in IgA nephropathy. You can email to kidneycares@hotmail.com  to get some tips to deal with them.

As protein in urine and swollen ankles result from kidney impairment in IgA nephropathy,to control them fundamentally, treatment should be used to treat kidney as a whole.If the kidney barrier function can be reversed,the associated symptoms will be controlled fundamentally.