Reoccurrence Rate of FSGS after Kidney Transplant

Reoccurrence rate of FSGS after kidney transplant is very high and it ranges from 20% to 66% due to different variants of focal segmental glomerulosclerosis. Because of its high reoccurrence rate, many FSGS patients are hesitating about whether they will receive kidney transplant.

FSGS is a major cause of Nephrotic Syndrome in children and adolescents, as well as an important cause of kidney failure in adult. Different from other kidney diseases like Diabetic Nephropathy and Polycystic Kidney Disease, diagnosis of FSGS needs renal biopsy. Kidney Tansplant is a conventional treatment for failed kidney. In theory, after kidney transplant, kidney failure patients need not to do dialysis; however, because of the special pathological changes, FSGS patients are not suitable for kidney transplant as it always comes back.

When FSGS develops to kidney failure, dialysis and kidney transplant may be the last two methods to further life. But due to the high reoccurrence rate of FSGS, dialysis may be the last option for FSGS patients. To avoid this bad consequence, early treatment is very necessary.

Timely treatment halts FSGS progresses to kidney failure easily. In early stage of FSGS, there is no too much glomeruli are involved and at that moment, as long as we repair damaged glomeruli and then protect healthy renal cells from being damaged effectively, further kidney damages will be prevented and also kidney failure will be avoided effectively.

Kidney transplant, as the last option for kidney failure patients, actually is not a perfect method for dealing with failed kidneys. Kidney transplant is a medical procedure, during which a healthy kidney is put into patient's body to replace the failed kidney. It indeed work in helping our body to discharge wastes, but it fails to remove causes of kidney failure. Therefore, after kidney transplant, kidney problem occurs easily if patients do not take any remedial measures aiming at causes of kidney disease.

For patients with FSGS in early stage, finding the root causes and then removing them is very essential, because only in this way, can FSGS be stopped radically and can kidney failure be avoided effectively. No kidney failure, no kidney transplant and of course no reoccurrence rate of FSGS.