Management of Proteinuria in FSGS

Proteinuria, as a dominant symptom of kidney problem, is not strange to FSGS patients. FSGS is a medical term that describes pathological changes of kidney. Its full name is Focal Segmental Glomerulosclerosis which means some glomeruli are damaged partly, not totally.

Glomerulus is famous for its filtration function, by means of which nutrition like protein can be kept in body effectively and meanwhile wastes are discharged. When glomeruli are damaged, renal filtration function is impaired, as a result of which, protein leak out and get out of patient's body with urine. This is the general process that how proteinuria in FSGS is formed.

As the dominant symptom of FSGS, proteinuria is also contributable for the quick progression of kidney damages. In addition, due to impaired filtration function, more and more protein leak out, which can cause malnutrition, poor immunity and hypoproteinemia and so on. From this point of view, controlling proteinuria is not only helpful for slowing down FSGS, but also help to avoid other related `diseases.

Well-planed diet is helpful for FSGS to have a good prognosis. With proteinuria, FSGS patients need to follow low-protein diet, because the more protein that patients ingest, the more protein get into urine and also the more serious the proteinuria is. In daily life, FSGS patients can ingest moderate high quality protein to meet the physical demand and that kind of protein can can be found in lean meat, egg white, milk and fish and so on.

Proteinuria is just one of the clinical manifestation of FSGS and can not be treated as the target.

Protein get into urine because of damaged glomeruli, so repairing these glomeruli and then recovering their filtration function is the best method to remit proteinuria.