FSGS: High Creatinine Level And Bubbles In Urine

FSGS is a common type of nephrotic syndrome in both adults and children. Scarring and fibrosis of part glomeruli causes the loss of kidney functions. The glomerular filtration membrane will be damaged. As a result, metabolic wastes and toxins can not be removed. Instead, useful substances such as proteins and red blood cells in the blood will be leaked into urine.

When abnormal proteins pass through the glomeruli, patients can find noticeable bubbles in their urine. Nephrotic syndrome is the most common and early clinical symptom of FSGS and about 2/3 patients will have massive proteinuria and serious edema. The severity of bubbles in urine vary from person to person and daily protein in urine can be 1-30g. Long term excess bubbles in urine can cause a series of problems such as swelling, hyperlipidemia, hypoalbuminemia, etc. What is more, proteinuria is an independent risk factor for FSGS patients. Long term proteinuria will in turn damage the glomerular basement membrane and further worsen renal damages.

Medicines for treating bubbles in urine include steroids, cytotoxic drugs, immunosuppressants, high pressure drugs, diuretics, etc. Bubbles in urine can be reduced after using these drugs and medicines. But it has been reported that some patients begin to have high creatinine after using these drugs for a period of time or their high creatinine is even worsened.

One reason is that their illness conditions become worse and further kidney functions are lost even though symptoms are temporarily controlled. Another reason is that these drugs have caused renal damages. Many drugs that are prescribed for FSGS patients have potential nephrotoxicity, therefore it is very necessary to have close monitoring of creatinine level in the blood so as to have early detection if these drugs cause damages to renal functions.

Serum creatinine is a good indicator of kidney damages and kidney functions. If creatinine level continues to become higher and higher, it means that kidney functions are declining, therefore early and proper treatment should be sought.

While seeking treatment for bubble urine and other symptoms of FSGS, one principle is to protect residual kidney function and avoid potential renal toxicity. Chinese medicines are more natural for treating bubbles in urine, lowering high creatinine and protecting kidney functions. Consult a professional practitioner of Chinese medicines and choose more natural remedies.