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How Fast do Kidneys Deteriorate with Diabetes

2012-10-31 16:01

Kidney disease as a chronic diabetic complication is that can develop into kidney failure if not prevented or treated at early course. For people with Diabetes, once they experience such renal symptoms as proteinuria and swelling, they need to do under an expert doctor's advice to delay or prevent fast deterioration of their kidney condition.

How fast do kidneys deteriorate with Diabetes? Diabetics once diagnosed as kidney disease are rather concerned how long would they delay progression of diabetic kidney disease and wonder if they have chance to improve their kidney condition. According clinical trials, slight damage to the kidneys may begin from the early course since diabetes is diagnosed, but may take years to make the disease to develop into an obvious condition.

Diabetic Nephropathy is microvascular disease caused by long-term or poorly controlled Diabetes. As we know, Diabetes with persistent high blood sugar can over time damage filteirng cells of the kidneys called as glomeruli. In the very beginning, Diabetes causes high filtration and high perfusion of the kidneys, thus making glomerular filtration rate(GFR) higher than normal. In the second stage of Diabetic Nephropathy, Diabetes causes thicking of glomerular basement membrane, and the mild pathological change of the kidneys may cause microalbuminuria after Diabetics do exercise or weakness. However, the microalbuminuria is slight and transistent, so the disease is hard to be detected.

Persistent microalbuminuria is a typical symptom of stage 3 Diabetic Nephropathy. People only by doing microalbuminuria test can detect the symptom. In this microalbuminuria stage, people by careful management of blood sugar and blood pressure may reverse the disease, but not necessarily back to normal. After the microalbuminuiria stage glomerular cell damage will be further worsened and thus it will cause persistent proteinuria. This will be reflected as the foams(bubbles) in urine which accompanies swelling in limbs, eyelids, ankles, face, etc. According to American Joslin report, average Diabetes course till presence of proteinuria is 17 years, and once people with Diabetes experience persistent clinical proteinuria, kidney function may get irreversibly decline. After the proteinuria stage, verage lifespan among people with Diabetes is 10 years and approximately 25% Diabetics develop into kidney failure within 6 years.

The clinical findinds suggest that Diabetic Nephropathy tend to deteriorate faster than kidney disorders. Combined diabetic complications such as retinopathy, heart disease and feet problems greatly affect the prognosis in Diabetics. Current deta only provides a general referance as to how fast kidney disease deteriorate with Diabetes. People with Diabetes should note the severity of kidney disease. Anyway, early prevention, diagnosis and treatment are most essential in improving the prognosis for Diabetic Nephropathy. Management of blood pressure and blood sugar, controlling proteinuria and preventing diabetic complications may effectively delay, but only block further deterioration of diabetic kidney disease. Only if injured renal cells are repaired and kidney conditon gets improved can Diabetics with kidney disease stop further renal fibrosis and live healthily. Combining traditional Chinese medicines with western medicines have proven by some clinical trials to achieve targeted treatment effects and avoid hazards of kidney failure.


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