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Are There Genetic Factors Causing Diabetic Nephropathy

2014-10-02 01:47

Are There Genetic Factors Causing Diabetic NephropathyWhich genetic factors can lead to Diabetic Nephropathy (DN)? In DN susceptibility testing, many researches deem that genetic factors play an important role in the occurrence and development of diabetic nephropathy. Well, the following article will introduce what genetic factors can lead to DN.

1. Angiotensin converting enzyme (ACE)

Gene polymorphism of ACE is related to the occurrence of diabetic nephropathy. Aldose reductase, sorbitol dehydrogenase: increased aldose reductase activity in red blood cells is the susceptibility factor of diabetic nephropathy, while the reduced sorbitol dehydrogenase activity makes patients at a higher risk of kidney disease.

2. Primary high blood pressure

Diabetic Nephropathy patients’ blood pressure in parents with diabetes is obviously higher patients without diabetic nephropathy.

3. N-deacetylase

Decreased heparan sulfate proteoglycan (Hs-PG)can lead to protein in urine and progressively enlarged glomerular mesangial area.

The characteristic therapy in our hospital is on the basis of motherland medicine theory of yin and yang five elements and the overall concept, combined with modern medical immune balance theory, applied the lastest scientific research achievements and combined with western medicines and Chinese Medicines to treat chronic kidney disease. The advantages of combination of western medicines and Chinese medicines is to alleviate the side effects of steroids. Also it can also reduce the dosage of steroids, restore the function of adrenal gland as well as reduce their debt.

There are three functions of combination with western medicines and Chinese medicines including playing an adjuvant role in the treatment, reduce side effects of western medicines, consolidating the effects and reduce recurrence.

If you still have doubts, you can consult our online doctor or leave us a message to kidneycares@hotmail.com. Renal expert will answer your question online.

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