Plasma Exchange Helps Lower Creatinine Level

Plasma exchange is one kind of blood purification technology which is to separate plasma containing toxins or pathogenic materials from the blood. In this treatment, the patient’ blood will be led into a plasma exchange machine, the separated plasma will be discarded and fresh plasma or substitutes will be supplied.

Plasma exchange can help discharge soluble immune complexes, some antibodies, various metabolic wastes and toxins, pathogenic factors so as to create a clean and favorable internal environment for further treatments and medicines to take better effects. And it has good curative effects especially in short term.

After the application of plasma exchange, the levels of serum creatinine and blood urea nitrogen (BUN) can be lowered. What is more important, it can not only clear small and moderate molecular toxins and wastes but also large molecular wastes such as proteins and immune complex especially the toxins that combine with proteins, so it has higher clearance rate that that of hemodialysis, blood filtration and blood perfusion. At the same time, it can replace some functions of the liver and supply essential substances that the body needs such as albumins, blood coagulation factors, etc.

At the same time of plasma exchange, hormones and immunosuppressant should be combined to ensure safety and effects because plasma exchange can only remove the existing immune complexes in the body but can not inhibit their continuous formations. That is to say plasma exchange can not solve the underlying cause of high creatinine, therefore patients should not ignore dealing with what cause kidney damages and increased creatinine level.

Besides lowering serum creatinine level, plasma exchange can be applied to treat all case of poisoning, weather it is due to chemicals, medicines, foods or bites. Once it is diagnosed in clinic, plasma exchange can be adopted and it can clear the toxins outsides quickly. Weather the toxins combine with protein and blood fat or dissolve in the plasma, plasma exchange can eliminate them in short time. The effects are even better for those that are combined with proteins and blood lipid.

In case of lupus nephritis, purpura nephritis, IgA nephropathy or acute rejections after kidney transplant and if hormones and other immunosuppressant can not control the illness conditions, plasma exchange can be adopted. It is effective on alleviating clinical symptoms and protecting kidney functions.