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Long term high blood sugar will cause damages to renal intrinsic cells and weaken the kidney function of detoxification. As a result, the metabolic wastes and toxins can not be discharged and they will accumulate in the body and cause increased levels of creatinine, urea nitrogen and uric acid, etc. Increased creatinine is a common sign in the end stage of diabetic nephropathy. It is an indicator of worsening of illness conditions and also a signal of effective treatments.
As a renal replacement therapy, dialysis can help lower creatinine and alleviate damages to the kidneys and the body. However it is just a machine to replace the kidney’s functions and it can not treat the pathological damages, not to say prevent the progression of the illness conditions. If patients only rely on dialysis and the remaining functional nephrons will cease work and the remaining kidney functions will be gradually lost. That does not to say patients should not take dialysis which can help save life if taken at the right time. Only that patient should seek more effective treatments besides dialysis.
As for effective treatments for diabetic nephropathy, there are 3 aspects that need to be noted.
1. Control blood sugar. Diabetic nephropathy is the most common complication of diabetes and the renal damages are caused by long term badly controlled high blood sugar. The first step should maintain the blood sugar at a stable level and this can help prevent further kidney damages.
2. Close monitoring and timely treatments of complications. Sometimes it is not the high creatinine or the disease itself that lead to death but the complications. Therefore it is very important to have close observation of complications and have effective prevention measure and timely treatments.
3. Control creatinine, blood in urine, protein in urine and repair kidney damages. The true treatments for diabetic nephropathy should consist of treating symptoms and repairing damages tissues in the kidneys.
