Kidney Disease And High BUN

The level of BUN (blood urea nitrogen) is one important measurement of kidney functions. It is the end product of protein metabolism and the kidney is the main organ to excrete urea nitrogen from the blood.

Same with serum creatinine, in the early stage of renal impairments, BUN levels can be within normal range. Only when patients have less than 50% kidney functions can there be elevation of BUN.

Many renal parenchymal diseases can cause high BUN such as glomerulonephritis, interstitial nephritis, acute and chronic renal failure, renal space-occupying lesions and destructive lesions can all cause BUN to elevate. Of cause, many extra-renal factors can also be possible causes such as infections, gastrointestinal bleeding or hyperthyreosis, etc. If all the extra-renal causes can be ruled out, BUN higher than 60 is one of the diagnosis indicators of kidney failure.

For kidney disease patients, there can be 2 cases of high blood urea nitrogen. The most common case is renal dysfunction including acute renal injuries and chronic kidney disease. When renal functions are impaired, excess urea and urea nitrogen can not be discharged efficiently from the blood. Urea nitrogen will accumulate in the blood and cause high BUN. The other case is often transient increase of BUN such as acute nephritis, nephrotic syndrome with severe edema. Because low urine output can not help flush the urea nitrogen with urine.

High BUN is often accompanied by high creatinine and the root cause is microcirculation disorder, glomerular sclerosis and impairment of the basement membrane. Only if these root problems are solved can high BUN be effectively treated and further relapse be prevented.

Micro-Chinese Medicine Osmotherapy can help promote blood circulation and increase blood flow to the kidneys. The states of renal ischemia and renal hypoxia can be improved and the process of renal fibrosis can be prevented or slowed. Active ingredients in Chinese medicines can also help repair damaged glomerular basement membrane so as to help protect kidney functions and promote renal excretion of blood urea nitrogen and other harmful wastes and toxins.